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OCR: tant Several forms of xanthomata give impo clinical clues to the nature of the underl pathophysiological defect. Thus, tendon xanthomata typically occur in familial efective apohypercholesterolaemia and in familial d or the B. Their presence in the Achilles tendon extensor tendons of the hand (Fig. 6.19) ractions of pathognomonic of genetic defects in inte lomata are LDL with its receptor. Occasionally, xant omata are seen on the patellar tendon. Since xanth e sites is often subtle, careful examination of thes required for their detection.